Following
the news that bird flu has spread into Russia, swissinfo spoke to expert
Christian Leumann about the virus and its consequences for humans.
Swiss officials announced last week
that they had started an avian flu information campaign for poultry farmers.
The first Russian cases of bird flu
were detected in a Western Siberian region in July, having seemingly spread from
southeast Asia where more than 50 people have died from the virus.
On Thursday the Federal Veterinary
Office confirmed it had started an information campaign to raise awareness about
the virus among poultry farmers. It extended the ban on birds and poultry from
Asian countries to Russia and Kazakhstan earlier this month.
The
Federal Health Office has also announced that it is to build a reserve of
vaccine to protect up to 100,000 people against the avian virus.
The bird flu virus is known to be
particularly aggressive and can be transmitted to humans. It is said to be fatal
in 50 per cent of cases, compared with just one per cent for normal strains of
flu.
Leumann, a professor of bioorganic
chemistry at Bern University, explained how the virus is transmitted between
species and what can be done to contain it.
swissinfo: Why is it that many flu
viruses originate in southeast Asia?
Christian Leumann: Flu viruses
spread and mutate particularly fast in regions where birds, people and other
animals live together in a small, agricultural areas which are not subject to
the best hygienic conditions. This is the case in southern China for example.
swissinfo: The flu virus is in
constant mutation. How come the virus, which is normally transmitted between
animals, is now being found in humans?
C.L.: This is nothing new – viruses
have always done this. The transmission of the flu virus between different
species has been particularly well researched.
Flu viruses develop and change
through mutations and individual forms of these viruses can suddenly jump
between species. In the bird flu case only the virus H5N1 affects humans as well
as birds.
swissinfo: What happens then?
C.L.: These originally animal
viruses can change more quickly through the genetic exchange with human flu
viruses. This leads to new forms of viruses, which are harder for the body's
immune system to manage.
swissinfo: There has been a lot of
talk the drug Tamiflu. How well can it fight bird flu?
C.L.: Tamiflu at the moment stops
viral reproduction. There are not yet any resistance problems. Viruses change
quickly and often become resistant to medications. It's the same as with
antibiotics.
If a medication is taken as a precautionary measure, or much worse, put into
poultry feed, the virus will certainly become more resistant more quickly. Such
behaviour is irresponsible and does not conform to international standards.
swissinfo: Is this the reason
Tamiflu is only available on prescription?
C.L.: This could be one of the
reasons. In any case this is a prime example of the necessity of being careful
with one of the few medications that works against the virus.
swissinfo: Is this careful approach
particularly important at the moment given that there aren't any vaccines that
work yet?
C.L.: Yes because the current
viruses are considered to be particularly virulent. For birds they mean almost
certain death.
Finding a vaccine against these new
viruses still needs time – six months or longer. This reminds me of what happed
around the Severe Acute Respiratory Syndrome (Sars) scare, where a vaccine was
also needed.
swissinfo-interview: Alexander
Künzle